Slay the Spire 2 character tier list and how to unlock them

How do you unlock all Slay the Spire 2 characters? With five characters to pick from, each with their own unique playstyle, it could take you hundreds of hours to master everyone in the game. Before you even consider how to play the other STS 2 characters, you'll have to unlock them first, and with the new Timeline section of the main menu, this is a bit more involved than you might be used to. New Slay the Spire 2 unlocks like additional cards, relics, and potions require certain criteria to be met, and the characters are no different in the roguelike game. We've broken down the best characters in Slay the Spire 2 with a handy tier list, along with their unlock requirements in case you still haven't acquired everyone.