Researchers Uncover a Hidden Molecular Machine Parasites Need To Survive

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Three Dimensional Structure of the Trans SpliceosomeResearchers have visualized two key stages of RNA processing in parasites that cause diseases such as sleeping sickness, Chagas’ disease, and leishmaniasis. For nearly 40 years, scientists have known that trypanosomatid parasites depend on an unusual system for processing RNA. Now researchers have captured that machinery at near-atomic resolution, showing how its components assemble and [...]
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