Metformin changes blood metal levels in humans, offering further insight into its mechanism of action (Copper, iron, & zinc)

The widely used diabetes drug metformin changes blood metal levels in humans. The study is an important step in understanding the drug's many actions and designing better ones in the future. Metformin is the most widely prescribed diabetes drug in the world. Apart from lowering blood sugar levels, it is also known to have a broad range of beneficial side effects such as against tumors, inflammation and atherosclerosis. However, although it has been used for more than 60 years now, its mechanism of action is still not clear, hampering the development of even better drugs against these conditions. Ogawa Wataru...